The chances of spontaneous conception decline with age, more so from the mid-thirties onwards. It is estimated that women older than 40 only have a 5% chance of conception with every cycle. This is in great contrast to women in late 20s and early 30s, whose chances of conception are 4 to 5 times higher. By the time you hit 45 years, the chances of conception with your own eggs are almost nil. It doesn’t end there, you also have higher chances of suffering a miscarriage. And pregnancy-related complications also occur more commonly.